Advantages

● Safer: The microchannel reactors has a low total liquid holdup, a large specific surface area, and a high heat transfer efficiency. It can remove a large amount of heat generated by the nitration reaction in time, reduce the risk of reaction.

● More efficient: The fluid in the microchannel is in a highly turbulent state, the reactants are mixed quickly and evenly, make reaction and production more efficient. It will more obvious for some nitration reactions that are limited by mass transfer.

● Better quality: The reaction conditions are easy to accurately control, such as temperature, pressure, material ratio, etc., which can make the reaction proceed in a more stable environment, reduce the occurrence of side reactions, and improve the product purity.

● Greener: Reduce raw material usage and energy consumption, reduce waste acid and the treatment costs, green and Environmentally Friendly.

● More flexible: Flexible and versatile system designed for process development, and easy for scale-up process from laboratory research to industrial production.

Microreactors to be used Nitroglycerine Production

The nitroglycerine is of pharmaceutical grade and used as medicine for acute cardiac infarction. This demands high selectivity and low levels of impurity.

First achieved the reaction in a microreactor. In the second step adding a purification unit for washing and drying.

1. Mix concentrated sulfuric acid and nitric acid through a low-temperature microreactor chip;

2. Input glycerol and dichloromethane into the mixer;

3. The mixed acid solution is distributed to the reaction chip through a distributor to react with glycerol;

4. The reaction product is mixed with cooled water to quench, and then extracted and dried.